Patented Happy Banana® Extract
Finally, the sleep that your body deserves
DISCOVER AMBROSESleep regularity is the habit experts WISH YOU KNEW
Ambrose® is a physiological approach to sleep – using patented Happy Banana® extract to naturally support circadian rhythm alignment, melatonin synthesis, and restorative sleep without sedation or dependency.
What you need to know
Irregular sleep is a SILENT EPIDEMIC
- Irregular sleep increases cardiovascular event risk by approximately 2× compared to consistent sleepers.
- Aim for 7-9 hours of sleep nightly, with consistency being just as important as duration.
- Consistent sleep timing supports circadian and metabolic health.
- Adults with highly variable sleep timing show a 53% higher risk of dementia (American Academy of Neurology, 2023).
- Sleep is now considered a core pillar of health, alongside diet and exercise.
7 - 9 hrs
Recommended nightly sleep, with consistency equally critical.
Sleep Foundation
2×
Higher CVD risk with irregular sleep patterns.
NIH/JACC Summary (2020)
53%
Higher dementia risk in irregular sleepers.
Ammerican Academy of Neurology (2023)
Mortality
Risk due to constant irregular sleep.
UK Biobank mortality analysis
Poor sleep timing – not just duration, is increasingly linked to cardiovascular disease, dementia, and premature mortality. Helping people achieve consistent sleep schedules may be one of the most impactful interventions in primary care.
CIRCADIAN ALIGNMENT VS MISALIGNMENT

Current pharmacologic options may temporarily alleviate this problem, but they may cause undesirable side effects such as: Daytime Sedation, Dependence or Tolerance and Cognitive impairment.
Mechanism of action
A physiological pathway to NATURAL MELATONIN SYNTHESIS
Ambrose® contains Hydroxyanigorufone from patented Happy Banana® extract, which upregulates the complete enzymatic cascade from tryptophan to melatonin — supporting the body’s own endocrine system rather than bypassing it.
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+ Happy Banana® Extract (Hydroxyanigorufone source)
+ L-Glutamine — supports neurotransmitter balance
+ Green Tea Extract — antioxidant and neuroprotective support
+ Chewable tablet form — convenient pre-bedtime dosing
RCT Trial Summary
Randomized · Double-blind · Placebo-controlled
4 wks
Duration
50
Adult participants
(18–65)
1.5g
Daily dose before bedtime
Clinical Evidence
Proven results in a RIGOROUS RCT
A 4-week randomized, double-blind, placebo-controlled trial in adults aged 18–65 with confirmed insomnia demonstrated significant improvements in melatonin synthesis, sleep timing, and daytime function.
Melatonin Levels
Serotonin Levels
Night–day Melatonin Difference
Daytime Drowsiness
Nocturia
WHY AMBROSE®
A better alternative to CONVENTIONAL OPTIONS
Most sleep aids work by forcing the body into submission. Whether through sedatives that suppress the nervous system or synthetic melatonin that replaces your natural hormones, conventional options often ignore the root of the problem. Ambrose® takes a different approach by working with your biology, not against it. By upregulating the natural enzymatic pathways, it triggers your body to produce its own melatonin endogenously.
The result? Genuine circadian restoration, not just sedation.
The Ambrose® Advantage
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Physiological Restoration: Enhances your body’s natural chemistry rather than relying on external replacements.
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Clinically Proven Results: Delivers a 209% improvement in the night-day melatonin difference, the primary driver of a healthy sleep-wake cycle.
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Zero Trade-offs: Achieve deep, restorative rest with:
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No daytime grogginess or “hangover” effect.
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No risk of dependency or habit-formation.
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No cognitive impairment or mental fog.
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The Clinical Choice: A mechanistically distinct option for long-term use that addresses root-cause circadian dysregulation rather than just masking symptoms.
Experience better sleep that is better tolerated, more physiologically sound, and designed for your long-term wellness.
Results
Improved sleep readiness and circadian synchronization.
Benefits
Improved sleep physiology, naturally.
Internationally recognised INNOVATION in sleep science
2013
GOLD
International Exhibition of Inventions of Geneva (+ Special Prize)
2013
SILVER
Inventeco International
Invention Show
2013
SILVER
International Innovation & Invention Conference
2013
SILVER
World Genius Convention &
Education Expo
Table of comparison
| Property | Ambrose® | Benzodiazepines | Z-drugs (Zolpidem etc.) | Exogenous Melatonin |
|---|---|---|---|---|
| Dependency risk | None | High | Moderate | None |
| Daytime sedation | Reduced −13.9% | Common | Common | Varies |
| Cognitive impairment | None observed | Significant | Moderate | Minimal |
| Supports natural melatonin | Upregulates synthesis | No | No | Replaces it |
| Circadian synchronisation | Yes — full pathway | No | No | Partial |
| Reduces nocturia | −19% in RCT | — | — | — |
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SAFETY & TOLERABILITY
Designed for real-world PATIENT ADHERENCE
Ambrose® is well tolerated in clinical trials with no significant adverse events reported. Its physiological mechanism means there is no external melatonin loading – only natural upregulation.

RECOMMENDED DOSAGE
Chewable tablet — banana extract with green tea
2 tablets
Per Day · Taken 2 hours before bedtime · Total 1.5g · No food restrictions.
- Onset of benefit observable from week 2–4 with consistent use.
- Suitable for adults aged 18–65 with insomnia or circadian disruption.
- No known interactions – consult full prescribing information.
Achieve better sleep, naturally.
Request samples, detailing materials, or arrange a meeting with an Ambrose® representative to learn how to integrate natural circadian support into your practice.