Finally, the sleep that your body deserves

DISCOVER AMBROSE

Sleep regularity is the habit experts WISH YOU KNEW

Ambrose® is a physiological approach to sleep – using patented Happy Banana® extract to naturally support circadian rhythm alignment, melatonin synthesis, and restorative sleep without sedation or dependency.

Patented Happy Banana® Extract

RCT – 4 weeks Double-blind Clinical Trial

Gold Award – Geneva Inventions 2013

No Dependency or Tolerance

Reduced Daytime Drowsiness

50 Adults · Placebo-Controlled

What you need to know

Irregular sleep is a SILENT EPIDEMIC

7 - 9 hrs

Recommended nightly sleep, with consistency equally critical.

Sleep Foundation

Higher CVD risk with irregular sleep patterns.

NIH/JACC Summary (2020)

53%

Higher dementia risk in irregular sleepers.

Ammerican Academy of Neurology (2023)

Mortality

Risk due to constant irregular sleep.

UK Biobank mortality analysis

Poor sleep timing – not just duration, is increasingly linked to cardiovascular disease, dementia, and premature mortality. Helping people achieve consistent sleep schedules may be one of the most impactful interventions in primary care.

CIRCADIAN ALIGNMENT VS MISALIGNMENT

Illustration of alignment vs misalignment for systoic blood pressure and melatonin rise and fall during a 24 hour window.

Current pharmacologic options may temporarily alleviate this problem, but they may cause undesirable side effects such as: Daytime Sedation, Dependence or Tolerance and Cognitive impairment.

Mechanism of action

A physiological pathway to NATURAL MELATONIN SYNTHESIS

Ambrose® contains Hydroxyanigorufone from patented Happy Banana® extract, which upregulates the complete enzymatic cascade from tryptophan to melatonin — supporting the body’s own endocrine system rather than bypassing it.

 

ENZYME FUNCTION STATUS
TPH Converts Tryptophan → 5-HTP Increase
DDC Converts 5-HTP → Serotonin Increase
AANAT Converts Serotonin → Melatonin Increase
ASMT Final step of Melatonin synthesis Increase

Scroll to the right for more info

Key Ingredients

+ Happy Banana® Extract (Hydroxyanigorufone source)

+ L-Glutamine — supports neurotransmitter balance

+ Green Tea Extract — antioxidant and neuroprotective support

+ Chewable tablet form — convenient pre-bedtime dosing

RCT Trial Summary

Randomized · Double-blind · Placebo-controlled

4 wks

Duration

50

Adult participants
(18–65)

1.5g

Daily dose before bedtime

Clinical Evidence

Proven results in a RIGOROUS RCT

Melatonin Levels

+ 43.3%

Serotonin Levels

+ 13.9%

Night–day Melatonin Difference

+ 209%

Daytime Drowsiness

- 13.9%
- 19%

WHY AMBROSE®

A better alternative to CONVENTIONAL OPTIONS

Most sleep aids work by forcing the body into submission. Whether through sedatives that suppress the nervous system or synthetic melatonin that replaces your natural hormones, conventional options often ignore the root of the problem. Ambrose® takes a different approach by working with your biology, not against it. By upregulating the natural enzymatic pathways, it triggers your body to produce its own melatonin endogenously.

The result? Genuine circadian restoration, not just sedation.

The Ambrose® Advantage

  • Physiological Restoration: Enhances your body’s natural chemistry rather than relying on external replacements.

  • Clinically Proven Results: Delivers a 209% improvement in the night-day melatonin difference, the primary driver of a healthy sleep-wake cycle.

  • Zero Trade-offs: Achieve deep, restorative rest with:

    • No daytime grogginess or “hangover” effect.

    • No risk of dependency or habit-formation.

    • No cognitive impairment or mental fog.

  • The Clinical Choice: A mechanistically distinct option for long-term use that addresses root-cause circadian dysregulation rather than just masking symptoms.

Experience better sleep that is better tolerated, more physiologically sound, and designed for your long-term wellness.

Results

Improved sleep readiness and circadian synchronization.

Benefits

Improved sleep physiology, naturally.

Internationally recognised INNOVATION in sleep science

2013

GOLD

International Exhibition of Inventions of Geneva (+ Special Prize)

2013

SILVER

Inventeco International
Invention Show

2013

SILVER

International Innovation & Invention Conference

2013

SILVER

World Genius Convention &
Education Expo

Table of comparison

 

Property Ambrose® Benzodiazepines Z-drugs (Zolpidem etc.) Exogenous Melatonin
Dependency risk None High Moderate None
Daytime sedation Reduced −13.9% Common Common Varies
Cognitive impairment None observed Significant Moderate Minimal
Supports natural melatonin Upregulates synthesis No No Replaces it
Circadian synchronisation Yes — full pathway No No Partial
Reduces nocturia −19% in RCT

Scroll to the right for more info

SAFETY & TOLERABILITY

Designed for real-world PATIENT ADHERENCE

Ambrose® is well tolerated in clinical trials with no significant adverse events reported. Its physiological mechanism means there is no external melatonin loading – only natural upregulation.

No daytime sedation or next-day grogginess.

No dependency, tolerance, or withdrawal effects.

No cognitive impairment observed in RCT participants.

Reduced nocturia supports uninterrupted sleep.

Natural banana peel extract with established antioxidant and antimicrobial properties.

Ongoing clinical study (N20210303) investigating broader sleep quality improvements.

RECOMMENDED DOSAGE

Chewable tablet — banana extract with green tea

2 tablets

Per Day · Taken 2 hours before bedtime · Total 1.5g · No food restrictions.

  • Onset of benefit observable from week 2–4 with consistent use.
  • Suitable for adults aged 18–65 with insomnia or circadian disruption.
  • No known interactions – consult full prescribing information.

Achieve better sleep, naturally.

Request samples, detailing materials, or arrange a meeting with an Ambrose® representative to learn how to integrate natural circadian support into your practice.

Contact Us